DNA was analysed in individuals where mutation status is indicated | Two HGD variants were novel : c |
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Solactive AG uses its best efforts to ensure that the Index is calculated correctly | Consistent with its solvent-exposed, flexible nature, the c |
Humana Press, New York, NY.
wt indicates a wild-type allele in carriers | 1 La Du BN, Zannoni VG, Laster L, Seegmiller JE : The nature of the defect in tyrosine metabolism in alcaptonuria |
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The effect of the splicing variants was predicted using Splice Site Prediction by Neural Network SSPNN and Human Splicing Finder HSF | If this novel site is used, 84 bases can be included into HGD transcript between exons 9 and 10, causing insertion of 28 amino acids into HGD protein sequence c |