| Al-Muftah is also leading a project in collaboration with Dr | Konduru Sastry from Weil Cornel Medical College in Qatar to understand the molecular mechanisms underlying the development of prostate cancer into the castration-resistant state, with the aim of identify key pro- and anti-apoptotic molecules and microRNAs that render prostate cancer cells at advanced stage resistant to therapy |
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| Elucidating the mechanisms modulating triple negative breast cancer aggressiveness by dissecting intertumoral and intratumoral heterogeneity at the cellular and molecular levels, including immunophenotyping of the tumor microenvironment and identifying potential targets for the design of cancer immunotherapies | Mariam has taught several courses in general biology and molecular biology at the department of Biological and Environmental Sciences |
Furthermore, she focused on the generation of novel chimeric antigen receptors against the tumor associated antigen 5T4.
28| In February 2012, she was seconded to Qatar Biomedical Research Institute as a scientist to pursue her research interest | Join the 7,000 data-driven marketers who can demonstrate continued success in their social strategy, and its impact on their businesses with reliable, straight-forward insights |
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| Furthermore, she is interested in understanding how endogenous expression of the target antigen impacts the efficacy of this type of immunotherapy, particularly the effect of immunosuppressive cells T-regulatory cells and MDSCs and cytokines upon cancer therapy, with the aim of mimicking what really happens in patients | Keyhole presents you with trustworthy analytics and authenticated data to take the guesswork out of your influencer marketing campaigns |
Her PhD project was focused on the use of a fully autologous mouse model to study immune regulation towards 5T4 targeted immunotherapies.
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